Well, adafruit has python sample code. You likely need the node FT232H module to use it from JS.
https://www.npmjs.com/package/FT232H
Does it actually work - I have no idea - that board is also apparently out of stock :-)
Sample python code below
# Import standard Python time library.
import time
# Import GPIO and FT232H modules.
import Adafruit_GPIO as GPIO
import Adafruit_GPIO.FT232H as FT232H
# Temporarily disable the built-in FTDI serial driver on Mac & Linux platforms.
FT232H.use_FT232H()
# Create an FT232H object that grabs the first available FT232H device found.
ft232h = FT232H.FT232H()
# Configure digital inputs and outputs using the setup function.
# Note that pin numbers 0 to 15 map to pins D0 to D7 then C0 to C7 on the board.
ft232h.setup(7, GPIO.IN) # Make pin D7 a digital input.
ft232h.setup(8, GPIO.OUT) # Make pin C0 a digital output.
# Loop turning the LED on and off and reading the input state.
print 'Press Ctrl-C to quit.'
while True:
# Set pin C0 to a high level so the LED turns on.
ft232h.output(8, GPIO.HIGH)
# Sleep for 1 second.
time.sleep(1)
# Set pin C0 to a low level so the LED turns off.
ft232h.output(8, GPIO.LOW)
# Sleep for 1 second.
time.sleep(1)
# Read the input on pin D7 and print out if it's high or low.
level = ft232h.input(7)
if level == GPIO.LOW:
print 'Pin D7 is LOW!'
else:
print 'Pin D7 is HIGH!'