Hi, i had the same problem the last weeks. It looks like pm2 creates the startup script for systemd with wrong parameters. You should check if there exists a file “/etc/systemd/systemd/pm2-pi.service” In my case the file existed but contained the following lines: USER=root which should be USER=pi Environment=PM2_HOME=/root/.pm2 which should be Environment=PM2_HOME=/home/pi/.pm2 PIDFile=/root/.pm2/pm2.pid which should be PIDFile=/home/pi/.pm2/pm2.pid If the file does not exist you can create it with: sudo pm2 startup systemd -u pi But you need to check the values again after creating it. In the end you can enable the script with: sudo systemd enable pm2-pi.service The parts in described by @Chris are needed as well