Not directly.

MMM-ProfileSwitcher, A Profile/User/Layout Switching Module might give you a way of rigging it up.

For a first quick demo:
https://streamable.com/5s6bn

@rvdgeer do you have pm2 installed and configured? Oh looked above, you do. Well I have noticed even though logs show command error, it still works, I think it’s because node doesn’t surround commands in quotes.